John Mellencamp says daughter Teddi Mellencamp is 'really sick' from cancer battle

Teddi Mellencamp has been bravely battling stage four melanoma, but her father, singer John Mellencamp, says his daughter is “suffering.”

John appeared on the “Joe Rogan Experience,” saying, "I do have a daughter that's really sick. She's not f--king fine. She's got cancer in the brain. And she's suffering right now."

Teddi was diagnosed with stage two melanoma in 2022 and revealed in April 2025 that the cancer was at stage four after the disease metastasized to her lungs and brain, resulting in her having a 50-50 chance of survival.

In October 2025, “The Real Housewives of Beverly Hills” alum revealed that tests showed her cancer was “undetectable.” She has previously had 17 melanoma spots and four brain tumors removed, and immunotherapy helped shrink the growths “significantly."

Teddi told the iHeartRadio podcast “Two T's in a Pod,” "Just to give a little life update to you guys, I had my immunotherapy yesterday, and they did my scans, and at this point, there is no detectable cancer.”

She continued, "I still need to be on immunotherapy for another year, and I'm not considered in remission or anything like that. When they told me, I was in such shock, I was numb. So I'm still going to be having days when I'm feeling sick and stuff because I am still in immunotherapy, so I'm still fighting because you have to be.

"The way they [doctors] said it works, it's like one year, then two years, then at three years you're allowed to be considered... in remission. So, that was huge news yesterday. All the tumors continued to shrink and everything. It's been good. It's a good day."

Even with the good news, John says his daughter is still struggling and he hopes he can convince her to move “back home” to Indiana with her kids, daughters Slate, 12, and Dove, 5, and son Cruz, 11, from her marriage to estranged husband Edwin Arroyave.

"You can't say you're cancer-free with the type of cancer she's got for three years. So she has lesions in her brain, it went from her back, just a little, teeny spot on her. Over the last couple years it grew, and it got inside her brain and her lungs,” he told “Today.”

He added Teddi “has good days” and “feels good” until she undergoes her immunotherapy treatment, which makes her “feel like hell for about four days” before she feels “normal” again.

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